Vitreous haemorrhage
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Vitreous haemorrhage refers to bleeding into the vitreous, which is the transparent, gel-like substance that makes up most of the volume of the eye,
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It is located between the lens and the retina (i.e. within the posterior segment).
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Causes
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There are many causes; these can broadly be broken down as follows:
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posterior vitreous detachment
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the vitreous naturally shrinks with age as part of the degenerative processes of ageing
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as it shrinks, it pulls on the retina. this traction can then lead to a tear
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this causes vessels to bleed
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a break in the retina or retinal detachment may also occur
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proliferative retinopathy (retinal disease in which there is new, pathological vessel growth). Causes include:
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diabetic retinopathy
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retinal vein occlusion
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vasculitis
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trauma
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relating to systemic disease e.g. bleeding disorders, sickle cell disease
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Symptoms
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Symptoms of vitreous haemorrhage vary according to the location and size of the bleed
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Symptoms are typically sudden in onset and painless, and may include:
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flashes (photopsias)
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floaters
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visual blurring or haze
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more severe / dense haemorrhage -> severe loss of vision, visual field defects
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Investigations
- Slit lamp assessment of the fundus (back of the eye)
- in dense vitreous haemorrhage it may not be possible to see the structures at the back of the eye
- if this is the case, ultrasound (B-sound ultrasonography, a specific type used in ophthalmology) should be used
- this allows assessment for an underlying retinal tear or retinal detachment
Management
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Treat any underlying cause
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Observation for a short interval - sometimes can spontaneously clear
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Vitrectomy
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vitreous jelly and associated haemorrhage are cut / aspirated from the eye using instruments that are introduced through ports in the sclera
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the space left behind is then filled with fluid to maintain the pressure of the eye
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Intravitreal anti-VEGF injections
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used when there is an underlying proliferative retinopathy
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References
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Gong, D., Kozak, A., Shah, V.A. and Kim, L.A. (2019). Pars Plana Vitrectomy. [online] American Academy of Ophthalmology. Available at: https://eyewiki.aao.org/Pars_Plana_Vitrectomy [Accessed 16 Nov. 2023].
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Salmon, J. F. (2019) Kanski’s clinical ophthalmology. 9th edn. London, England: Elsevier Health Sciences.